Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses

Deregulation of ErbB signaling plays a key role in the progression of multiple human cancers. To help understand ErbB signaling quantitatively, in this work we combine traditional experiments with computational modeling, building a model that describes how stimulation of all four ErbB receptors with...

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Detalles Bibliográficos
Autores principales: Birtwistle, Marc R, Hatakeyama, Mariko, Yumoto, Noriko, Ogunnaike, Babatunde A, Hoek, Jan B, Kholodenko, Boris N
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2007
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132449/
https://www.ncbi.nlm.nih.gov/pubmed/18004277
http://dx.doi.org/10.1038/msb4100188

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132449/
https://www.ncbi.nlm.nih.gov/pubmed/18004277
http://dx.doi.org/10.1038/msb4100188

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