Chromosomes with Two Intact Axial Cores Are Induced by G(2 )Checkpoint Override: Evidence That DNA Decatenation Is not Required to Template the Chromosome Structure

Here we report that DNA decatenation is not a physical requirement for the formation of mammalian chromosomes containing a two-armed chromosome scaffold. 2-aminopurine override of G(2) arrest imposed by VM-26 or ICRF-193, which inhibit topoisomerase II (topo II)–dependent DNA decatenation, results i...

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Detalles Bibliográficos
Autores principales: Andreassen, Paul R., Lacroix, Françoise B., Margolis, Robert L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132461/
https://www.ncbi.nlm.nih.gov/pubmed/9008701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132461/
https://www.ncbi.nlm.nih.gov/pubmed/9008701

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