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Chromosomes with Two Intact Axial Cores Are Induced by G(2 )Checkpoint Override: Evidence That DNA Decatenation Is not Required to Template the Chromosome Structure
Here we report that DNA decatenation is not a physical requirement for the formation of mammalian chromosomes containing a two-armed chromosome scaffold. 2-aminopurine override of G(2) arrest imposed by VM-26 or ICRF-193, which inhibit topoisomerase II (topo II)–dependent DNA decatenation, results i...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1997
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132461/ https://www.ncbi.nlm.nih.gov/pubmed/9008701 |