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Rapid Plasma Membrane Anchoring of Newly Synthesized p59  (fyn): Selective Requirement for NH(2)-Terminal Myristoylation and Palmitoylation at Cysteine-3

The trafficking of Src family proteins after biosynthesis is poorly defined. Here we studied the role of dual fatty acylation with myristate and palmitate in biosynthetic transport of p59(fyn). Metabolic labeling of transfected COS or NIH 3T3 cells with [(35)S]methionine followed by analysis of cyto...

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Detalles Bibliográficos
Autores principales: Hof, Wouter van 't, Resh, Marilyn D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132482/
https://www.ncbi.nlm.nih.gov/pubmed/9060467