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Myelin-associated Glycoprotein Interacts with Neurons via a Sialic Acid Binding Site at ARG118 and a Distinct Neurite Inhibition Site

Inhibitory components in myelin are largely responsible for the lack of regeneration in the mammalian CNS. Myelin-associated glycoprotein (MAG), a sialic acid binding protein and a component of myelin, is a potent inhibitor of neurite outgrowth from a variety of neurons both in vitro and in vivo. He...

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Detalles Bibliográficos
Autores principales: Tang, Song, Shen, Ying Jing, DeBellard, Maria Elena, Mukhopadhyay, Gitali, Salzer, James L., Crocker, Paul R., Filbin, Marie T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132563/
https://www.ncbi.nlm.nih.gov/pubmed/9298990