Cargando…
Myelin-associated Glycoprotein Interacts with Neurons via a Sialic Acid Binding Site at ARG118 and a Distinct Neurite Inhibition Site
Inhibitory components in myelin are largely responsible for the lack of regeneration in the mammalian CNS. Myelin-associated glycoprotein (MAG), a sialic acid binding protein and a component of myelin, is a potent inhibitor of neurite outgrowth from a variety of neurons both in vitro and in vivo. He...
Autores principales: | Tang, Song, Shen, Ying Jing, DeBellard, Maria Elena, Mukhopadhyay, Gitali, Salzer, James L., Crocker, Paul R., Filbin, Marie T. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1997
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132563/ https://www.ncbi.nlm.nih.gov/pubmed/9298990 |
Ejemplares similares
-
Tenascin-C contains distinct adhesive, anti-adhesive, and neurite outgrowth promoting sites for neurons
Publicado: (1996) -
Inhibition of neurite outgrowth using commercial myelin associated glycoprotein-Fc in neuro-2a cells
por: Liu, Fu, et al.
Publicado: (2018) -
Insulin enhances neurite extension and myelination of diabetic neuropathy neurons
por: Pham, Vuong M., et al.
Publicado: (2022) -
The Glycosylation Site of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition in a Large Proportion of Patients
por: Marti Fernandez, Iris, et al.
Publicado: (2019) -
Sialic Acid Is Required for Neuronal Inhibition by Soluble MAG but not for Membrane Bound MAG
por: Al-Bashir, Najat, et al.
Publicado: (2016)