Cargando…

Surrogate Antigen Processing Mediated by TAP-dependent Antigenic Peptide Secretion

MHC class I proteins assemble with peptides in the ER. The peptides are predominantly generated from cytoplasmic proteins, probably by the action of the proteasome, a multicatalytic proteinase complex. Peptides are translocated into the ER by the transporters associated with antigen processing (TAP)...

Descripción completa

Detalles Bibliográficos
Autores principales: Gabathuler, Reinhard, Alimonti, Judie, Zhang, Qian-Jin, Kolaitis, Gerassimos, Reid, Gregor, Jefferies, Wilfred A.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132598/
https://www.ncbi.nlm.nih.gov/pubmed/9425150