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CENP-E Function at Kinetochores Is Essential for Chromosome Alignment

CENP-E is a kinesin-like protein that binds to kinetochores and may provide functions that are critical for normal chromosome motility during mitosis. To directly test the in vivo function of CENP-E, we microinjected affinity-purified antibodies to block the assembly of CENP-E onto kinetochores and...

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Detalles Bibliográficos
Autores principales: Schaar, B.T., Chan, G.K.T., Maddox, P., Salmon, E.D., Yen, T.J.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132614/
https://www.ncbi.nlm.nih.gov/pubmed/9396744