Ligation of Major Histocompatability Complex (MHC) Class I Molecules on Human T Cells Induces Cell Death through PI-3 Kinase–induced c-Jun NH(2)-terminal Kinase Activity: A Novel Apoptotic Pathway Distinct from Fas-induced Apoptosis

Ligation of major histocompatability complex class I (MHC-I) molecules expressed on T cells leads to both growth arrest and apoptosis. The aim of the current study was to investigate the intracellular signal pathways that mediate these effects. MHC-I ligation of human Jurkat T cells induced a morpho...

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Detalles Bibliográficos
Autores principales: Skov, Søren, Klausen, Pia, Claesson, Mogens H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132618/
https://www.ncbi.nlm.nih.gov/pubmed/9396757

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132618/
https://www.ncbi.nlm.nih.gov/pubmed/9396757

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