The Caspase-3 Precursor Has a Cytosolic and Mitochondrial Distribution: Implications for Apoptotic Signaling

Caspase-3–mediated proteolysis is a critical element of the apoptotic process. Recent studies have demonstrated a central role for mitochondrial proteins (e.g., Bcl-2 and cytochrome c) in the activation of caspase-3, by a process that involves interaction of several protein molecules. Using antibodi...

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Detalles Bibliográficos
Autores principales: Mancini, Marie, Nicholson, Donald W., Roy, Sophie, Thornberry, Nancy A., Peterson, Erin P., Casciola-Rosen, Livia A., Rosen, Antony
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132665/
https://www.ncbi.nlm.nih.gov/pubmed/9508780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132665/
https://www.ncbi.nlm.nih.gov/pubmed/9508780

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