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The Caspase-3 Precursor Has a Cytosolic and Mitochondrial Distribution: Implications for Apoptotic Signaling
Caspase-3–mediated proteolysis is a critical element of the apoptotic process. Recent studies have demonstrated a central role for mitochondrial proteins (e.g., Bcl-2 and cytochrome c) in the activation of caspase-3, by a process that involves interaction of several protein molecules. Using antibodi...
Autores principales: | Mancini, Marie, Nicholson, Donald W., Roy, Sophie, Thornberry, Nancy A., Peterson, Erin P., Casciola-Rosen, Livia A., Rosen, Antony |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132665/ https://www.ncbi.nlm.nih.gov/pubmed/9508780 |
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