Intracellular Localization of Phosphatidylinositide 3-kinase and Insulin Receptor Substrate-1 in Adipocytes: Potential Involvement of a Membrane Skeleton

Phosphatidylinositide (PI) 3-kinase binds to tyrosyl-phosphorylated insulin receptor substrate-1 (IRS-1) in insulin-treated adipocytes, and this step plays a central role in the regulated movement of the glucose transporter, GLUT4, from intracellular vesicles to the cell surface. PDGF, which also ac...

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Detalles Bibliográficos
Autores principales: Clark, Sharon F., Martin, Sally, Carozzi, Amanda J., Hill, Michelle M., James, David E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132698/
https://www.ncbi.nlm.nih.gov/pubmed/9490733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132698/
https://www.ncbi.nlm.nih.gov/pubmed/9490733

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