Mutant Rab7 Causes the Accumulation of Cathepsin D and Cation-independent Mannose 6–Phosphate Receptor in an Early Endocytic Compartment

Stable BHK cell lines inducibly expressing wild-type or dominant negative mutant forms of the rab7 GTPase were isolated and used to analyze the role of a rab7-regulated pathway in lysosome biogenesis. Expression of mutant rab7N125I protein induced a dramatic redistribution of cation-independent mann...

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Detalles Bibliográficos
Autores principales: Press, Barry, Feng, Yan, Hoflack, Bernard, Wandinger-Ness, Angela
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132709/
https://www.ncbi.nlm.nih.gov/pubmed/9490721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132709/
https://www.ncbi.nlm.nih.gov/pubmed/9490721

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