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Filipin-dependent Inhibition of Cholera Toxin: Evidence for Toxin Internalization and Activation through Caveolae-like Domains
The mechanism by which cholera toxin (CT) is internalized from the plasma membrane before its intracellular reduction and subsequent activation of adenylyl cyclase is not well understood. Ganglioside G(M1), the receptor for CT, is predominantly clustered in detergent-insoluble glycolipid rafts and i...
Autores principales: | Orlandi, Palmer A., Fishman, Peter H. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1998
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132770/ https://www.ncbi.nlm.nih.gov/pubmed/9585410 |
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