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Different cis-Regulatory DNA Elements Mediate Developmental Stage- and Tissue-specific Expression of the Human COL2A1 Gene in Transgenic Mice

Expression of the type II collagen gene (human COL2A1, mouse Col2a1) heralds the differentiation of chondrocytes. It is also expressed in progenitor cells of some nonchondrogenic tissues during embryogenesis. DNA sequences in the 5′ flanking region and intron 1 are known to control tissue-specific e...

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Detalles Bibliográficos
Autores principales: Leung, Keith K.H., Ng, Ling Jim, Ho, Ken K.Y., Tam, Patrick P.L., Cheah, Kathryn S.E.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132792/
https://www.ncbi.nlm.nih.gov/pubmed/9628886