Fab1p Is Essential for PtdIns(3)P 5-Kinase Activity and the Maintenance of Vacuolar Size and Membrane Homeostasis

The Saccharomyces cerevisiae FAB1 gene encodes a 257-kD protein that contains a cysteine-rich RING-FYVE domain at its NH(2)-terminus and a kinase domain at its COOH terminus. Based on its sequence, Fab1p was initially proposed to function as a phosphatidylinositol 4-phosphate (PtdIns(4)P) 5-kinase (...

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Detalles Bibliográficos
Autores principales: Gary, Jonathan D., Wurmser, Andrew E., Bonangelino, Cecilia J., Weisman, Lois S., Emr, Scott D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132800/
https://www.ncbi.nlm.nih.gov/pubmed/9763421

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132800/
https://www.ncbi.nlm.nih.gov/pubmed/9763421

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