Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg(2+) Ions

Bcl-2 family members either promote or repress programmed cell death. Bax, a death-promoting member, is a pore-forming, mitochondria-associated protein whose mechanism of action is still unknown. During apoptosis, cytochrome C is released from the mitochondria into the cytosol where it binds to APAF...

Descripción completa

Detalles Bibliográficos
Autores principales: Eskes, Robert, Antonsson, Bruno, Osen-Sand, Astrid, Montessuit, Sylvie, Richter, Christoph, Sadoul, Rémy, Mazzei, Gonzalo, Nichols, Anthony, Martinou, Jean-Claude
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132823/
https://www.ncbi.nlm.nih.gov/pubmed/9763433

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132823/
https://www.ncbi.nlm.nih.gov/pubmed/9763433

Ejemplares similares