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Bax-induced Cytochrome C Release from Mitochondria Is Independent of the Permeability Transition Pore but Highly Dependent on Mg(2+) Ions

Bcl-2 family members either promote or repress programmed cell death. Bax, a death-promoting member, is a pore-forming, mitochondria-associated protein whose mechanism of action is still unknown. During apoptosis, cytochrome C is released from the mitochondria into the cytosol where it binds to APAF...

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Detalles Bibliográficos
Autores principales:	Eskes, Robert, Antonsson, Bruno, Osen-Sand, Astrid, Montessuit, Sylvie, Richter, Christoph, Sadoul, Rémy, Mazzei, Gonzalo, Nichols, Anthony, Martinou, Jean-Claude
Formato:	Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 1998
Materias:	Regular Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132823/ https://www.ncbi.nlm.nih.gov/pubmed/9763433

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