Extracellular Matrix Survival Signals Transduced by Focal Adhesion Kinase Suppress p53-mediated Apoptosis

In many malignant cells, both the anchorage requirement for survival and the function of the p53 tumor suppressor gene are subverted. These effects are consistent with the hypothesis that survival signals from extracellular matrix (ECM) suppress a p53-regulated cell death pathway. We report that sur...

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Detalles Bibliográficos
Autores principales: Ilić, Duško, Almeida, Eduardo A.C., Schlaepfer, David D., Dazin, Paul, Aizawa, Shinichi, Damsky, Caroline H.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132850/
https://www.ncbi.nlm.nih.gov/pubmed/9786962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132850/
https://www.ncbi.nlm.nih.gov/pubmed/9786962

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