Genetic Evidence for ATP-dependent Endoplasmic Reticulum-to-Golgi Apparatus Trafficking of Ceramide for Sphingomyelin Synthesis in Chinese Hamster Ovary Cells

LY-A strain is a Chinese hamster ovary cell mutant resistant to sphingomyelin (SM)-directed cytolysin and has a defect in de novo SM synthesis. Metabolic labeling experiments with radioactive serine, sphingosine, and choline showed that LY-A cells were defective in synthesis of SM from these precurs...

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Detalles Bibliográficos
Autores principales: Fukasawa, Masayoshi, Nishijima, Masahiro, Hanada, Kentaro
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132924/
https://www.ncbi.nlm.nih.gov/pubmed/10037789

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132924/
https://www.ncbi.nlm.nih.gov/pubmed/10037789

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