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Microtubule-dependent Plus- and Minus End–directed Motilities Are Competing Processes for Nuclear Targeting of Adenovirus

Adenovirus (Ad) enters target cells by receptor-mediated endocytosis, escapes to the cytosol, and then delivers its DNA genome into the nucleus. Here we analyzed the trafficking of fluorophore-tagged viruses in HeLa and TC7 cells by time-lapse microscopy. Our results show that native or taxol-stabil...

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Detalles Bibliográficos
Autores principales: Suomalainen, Maarit, Nakano, Michel Y., Keller, Stephan, Boucke, Karin, Stidwill, Robert P., Greber, Urs F.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132937/
https://www.ncbi.nlm.nih.gov/pubmed/10037788