Activation of G(12)/G(13) Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets

Platelets respond to various stimuli with rapid changes in shape followed by aggregation and secretion of their granule contents. Platelets lacking the α-subunit of the heterotrimeric G protein G(q) do not aggregate and degranulate but still undergo shape change after activation through thromboxane-...

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Detalles Bibliográficos
Autores principales: Klages, Birgit, Brandt, Ursula, Simon, Melvin I., Schultz, Günter, Offermanns, Stefan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132941/
https://www.ncbi.nlm.nih.gov/pubmed/10037795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132941/
https://www.ncbi.nlm.nih.gov/pubmed/10037795

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