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Activation of G(12)/G(13) Results in Shape Change and Rho/Rho-Kinase–mediated Myosin Light Chain Phosphorylation in Mouse Platelets
Platelets respond to various stimuli with rapid changes in shape followed by aggregation and secretion of their granule contents. Platelets lacking the α-subunit of the heterotrimeric G protein G(q) do not aggregate and degranulate but still undergo shape change after activation through thromboxane-...
Autores principales: | Klages, Birgit, Brandt, Ursula, Simon, Melvin I., Schultz, Günter, Offermanns, Stefan |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1999
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132941/ https://www.ncbi.nlm.nih.gov/pubmed/10037795 |
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