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Interferon α Inhibits a Src-mediated Pathway Necessary for Shigella-induced Cytoskeletal Rearrangements in Epithelial Cells

Shigella flexneri, the causative agent of bacillary dysentery, has the ability to enter nonphagocytic cells. The interferon (IFN) family of cytokines was found to inhibit Shigella invasion of cultured epithelial cells. We show here that IFN-α inhibits a Src-dependent signaling cascade triggered by S...

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Detalles Bibliográficos
Autores principales: Duménil, G., Olivo, J.C., Pellegrini, S., Fellous, M., Sansonetti, P.J., Nhieu, G. Tran Van
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132965/
https://www.ncbi.nlm.nih.gov/pubmed/9817757