Release of cAMP Gating by the α6β4 Integrin Stimulates Lamellae Formation and the Chemotactic Migration of Invasive Carcinoma Cells

The α6β4 integrin promotes carcinoma in-vasion by its activation of a phosphoinositide 3-OH (PI3-K) signaling pathway (Shaw, L.M., I. Rabinovitz, H.H.-F. Wang, A. Toker, and A.M. Mercurio. Cell. 91: 949–960). We demonstrate here using MDA-MB-435 breast carcinoma cells that α6β4 stimulates chemotacti...

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Detalles Bibliográficos
Autores principales: O'Connor, Kathleen L., Shaw, Leslie M., Mercurio, Arthur M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132981/
https://www.ncbi.nlm.nih.gov/pubmed/9852165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132981/
https://www.ncbi.nlm.nih.gov/pubmed/9852165

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