Distinct Roles for the p110α and hVPS34 Phosphatidylinositol 3′-Kinases in Vesicular Trafficking, Regulation of the Actin Cytoskeleton, and Mitogenesis

We have examined the roles of the p85/ p110α and hVPS34 phosphatidylinositol (PI) 3′-kinases in cellular signaling using inhibitory isoform-specific antibodies. We raised anti-hVPS34 and anti-p110α antibodies that specifically inhibit recombinant hVPS34 and p110α, respectively, in vitro. We used the...

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Detalles Bibliográficos
Autores principales: Siddhanta, Uma, McIlroy, James, Shah, Amishi, Zhang, Yitao, Backer, Jonathan M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132989/
https://www.ncbi.nlm.nih.gov/pubmed/9852157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2132989/
https://www.ncbi.nlm.nih.gov/pubmed/9852157

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