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Activation of the MAP Kinase Pathway by FGF-1 Correlates with Cell Proliferation Induction While Activation of the Src Pathway Correlates with Migration

FGF regulates both cell migration and proliferation by receptor-dependent induction of immediate-early gene expression and tyrosine phosphorylation of intracellular polypeptides. Because little is known about the disparate nature of intracellular signaling pathways, which are able to discriminate be...

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Detalles Bibliográficos
Autores principales: LaVallee, Theresa M., Prudovsky, Igor A., McMahon, Grainne A., Hu, Xiaoguo, Maciag, Thomas
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133001/
https://www.ncbi.nlm.nih.gov/pubmed/9647656