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Stabilization and Localization of Xist RNA are Controlled by Separate Mechanisms and are Not Sufficient for X Inactivation

These studies address whether XIST RNA is properly localized to the X chromosome in somatic cells where human XIST expression is reactivated, but fails to result in X inactivation (Tinker, A.V., and C.J. Brown. 1998. Nucl. Acids Res. 26:2935–2940). Despite a nuclear RNA accumulation of normal abunda...

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Detalles Bibliográficos
Autores principales: Clemson, Christine Moulton, Chow, Jennifer C., Brown, Carolyn J., Lawrence, Jeanne Bentley
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133021/
https://www.ncbi.nlm.nih.gov/pubmed/9660859