Dislocation of Type I Membrane Proteins from the ER to the Cytosol Is Sensitive to Changes in Redox Potential

The human cytomegalovirus (HCMV) gene products US2 and US11 dislocate major histocompatibility class I heavy chains from the ER and target them for proteasomal degradation in the cytosol. The dislocation reaction is inhibited by agents that affect intracellular redox potential and/or free thiol stat...

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Detalles Bibliográficos
Autores principales: Tortorella, Domenico, Story, Craig M., Huppa, Johannes B., Wiertz, Emmanuel J.H.J., Jones, Thomas R., Ploegh, Hidde L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133060/
https://www.ncbi.nlm.nih.gov/pubmed/9679137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133060/
https://www.ncbi.nlm.nih.gov/pubmed/9679137

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