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Integration of Endothelial Cells in Multicellular Spheroids Prevents Apoptosis and Induces Differentiation

Single endothelial cells (EC) seeded in suspension culture rapidly undergo apoptosis. Addition of survival factors, such as VEGF and FGF-2, does not prevent apoptosis of suspended EC. However, when cells are allowed to establish cell–cell contacts, they become responsive to the activities of surviva...

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Detalles Bibliográficos
Autores principales: Korff, Thomas, Augustin, Hellmut G.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1998
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133072/
https://www.ncbi.nlm.nih.gov/pubmed/9832561