Cargando…

Dual Fatty Acylation of p59(Fyn) Is Required for Association with the T Cell Receptor ζ Chain through Phosphotyrosine–Src Homology Domain-2 Interactions

The first 10 residues within the Src homology domain (SH)–4 domain of the Src family kinase Fyn are required for binding to the immune receptor tyrosine-based activation motif (ITAM) of T cell receptor (TCR) subunits. Recently, mutation of glycine 2, cysteine 3, and lysines 7 and 9 was shown to bloc...

Descripción completa

Detalles Bibliográficos
Autores principales: Hof, Woutervan't, Resh, Marilyn D.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133112/
https://www.ncbi.nlm.nih.gov/pubmed/10209031