Budding Yeast Bub2 Is Localized at Spindle Pole Bodies and Activates the Mitotic Checkpoint via a Different Pathway from Mad2

The mitotic checkpoint blocks cell cycle progression before anaphase in case of mistakes in the alignment of chromosomes on the mitotic spindle. In budding yeast, the Mad1, 2, 3, and Bub1, 2, 3 proteins mediate this arrest. Vertebrate homologues of Mad1, 2, 3, and Bub1, 3 bind to unattached kinetoch...

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Detalles Bibliográficos
Autores principales: Fraschini, Roberta, Formenti, Elisa, Lucchini, Giovanna, Piatti, Simonetta
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133126/
https://www.ncbi.nlm.nih.gov/pubmed/10352016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133126/
https://www.ncbi.nlm.nih.gov/pubmed/10352016

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