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R-Ras Signals through Specific Integrin α Cytoplasmic Domains to Promote Migration and Invasion of Breast Epithelial Cells

Specificity and modulation of integrin function have important consequences for cellular responses to the extracellular matrix, including differentiation and transformation. The Ras-related GTPase, R-Ras, modulates integrin affinity, but little is known of the signaling pathways and biological funct...

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Detalles Bibliográficos
Autores principales: Keely, Patricia J., Rusyn, Elena V., Cox, Adrienne D., Parise, Leslie V.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133135/
https://www.ncbi.nlm.nih.gov/pubmed/10352023