Evidence for Apical Endocytosis in Polarized Hepatic Cells: Phosphoinositide 3-Kinase Inhibitors Lead to the Lysosomal Accumulation of Resident Apical Plasma Membrane Proteins

The architectural complexity of the hepatocyte canalicular surface has prevented examination of apical membrane dynamics with methods used for other epithelial cells. By adopting a pharmacological approach, we have documented for the first time the internalization of membrane proteins from the hepat...

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Detalles Bibliográficos
Autores principales: Tuma, Pamela L., Finnegan, Catherine M., Yi, Ji-Hyun, Hubbard, Ann L.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133136/
https://www.ncbi.nlm.nih.gov/pubmed/10352024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133136/
https://www.ncbi.nlm.nih.gov/pubmed/10352024

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