Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A(2)

Cytosolic phospholipase A(2) (cPLA(2)) mediates agonist-induced arachidonic acid release, the first step in eicosanoid production. cPLA(2) is regulated by phosphorylation and by calcium, which binds to a C2 domain and induces its translocation to membrane. The functional roles of phosphorylation sit...

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Detalles Bibliográficos
Autores principales: Gijón, Miguel A., Spencer, Diane M., Kaiser, Alan L., Leslie, Christina C.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133140/
https://www.ncbi.nlm.nih.gov/pubmed/10366595

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133140/
https://www.ncbi.nlm.nih.gov/pubmed/10366595

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