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Role of Phosphorylation Sites and the C2 Domain in Regulation of Cytosolic Phospholipase A(2)
Cytosolic phospholipase A(2) (cPLA(2)) mediates agonist-induced arachidonic acid release, the first step in eicosanoid production. cPLA(2) is regulated by phosphorylation and by calcium, which binds to a C2 domain and induces its translocation to membrane. The functional roles of phosphorylation sit...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
1999
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133140/ https://www.ncbi.nlm.nih.gov/pubmed/10366595 |