Combined Biochemical and Electron Microscopic Analyses Reveal the Architecture of the Mammalian U2 snRNP

The 17S U2 small nuclear ribonucleoprotein particle (snRNP) represents the active form of U2 snRNP that binds to the pre-mRNA during spliceosome assembly. This particle forms by sequential interactions of splicing factors SF3b and SF3a with the 12S U2 snRNP. We have purified SF3b and the 15S U2 snRN...

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Detalles Bibliográficos
Autores principales: Krämer, Angela, Grüter, Patric, Gröning, Karsten, Kastner, Berthold
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Regular Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133165/
https://www.ncbi.nlm.nih.gov/pubmed/10385517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133165/
https://www.ncbi.nlm.nih.gov/pubmed/10385517

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