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p21-Activated Kinase 1 (Pak1) Regulates Cell Motility in Mammalian Fibroblasts

The p21 (Cdc42/Rac) activated kinase Pak1 regulates cell morphology and polarity in most, if not all, eukaryotic cells. We and others have established that Pak's effects on these parameters are mediated by changes in the organization of cortical actin. Because cell motility requires polarized r...

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Detalles Bibliográficos
Autores principales: Sells, Mary Ann, Boyd, Jonathan T., Chernoff, Jonathan
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133181/
https://www.ncbi.nlm.nih.gov/pubmed/10330410