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Critical Role for Cholesterol in Lyn-mediated Tyrosine Phosphorylation of FcεRI and Their Association with Detergent-resistant Membranes

Tyrosine phosphorylation of the high affinity immunoglobulin (Ig)E receptor (FcεRI) by the Src family kinase Lyn is the first known biochemical step that occurs during activation of mast cells and basophils after cross-linking of FcεRI by antigen. The hypothesis that specialized regions in the plasm...

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Detalles Bibliográficos
Autores principales: Sheets, Erin D., Holowka, David, Baird, Barbara
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1999
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2133197/
https://www.ncbi.nlm.nih.gov/pubmed/10330413