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Identification of Protein p270/Tpr as a Constitutive Component of the Nuclear Pore Complex–attached Intranuclear Filaments

Using a monoclonal antibody, mAb 203-37, we have identified a polypeptide of M (r) ∼270 kD (p270) as a general constituent of the intranuclear filaments attached to the nucleoplasmic annulus of the nuclear pore complex (NPC) in diverse kinds of vertebrate cells. Using cDNA cloning and immunobiochemi...

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Detalles Bibliográficos
Autores principales: Cordes, Volker C., Reidenbach, Sonja, Rackwitz, Hans-Richard, Franke, Werner W.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134304/
https://www.ncbi.nlm.nih.gov/pubmed/9024684