Adenomatous Polyposis Coli Tumor Suppressor Protein Has Signaling Activity in Xenopus laevis Embryos Resulting in the Induction of an Ectopic Dorsoanterior Axis

Mutations in the adenomatous polyposis coli (APC) tumor suppressor gene are linked to both familial and sporadic human colon cancer. So far, a clear biological function for the APC gene product has not been determined. We assayed the activity of APC in the early Xenopus embryo, which has been establ...

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Detalles Bibliográficos
Autores principales: Vleminckx, Kris, Wong, Ellen, Guger, Kathy, Rubinfeld, Bonnee, Polakis, Paul, Gumbiner, Barry M.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134811/
https://www.ncbi.nlm.nih.gov/pubmed/9015311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134811/
https://www.ncbi.nlm.nih.gov/pubmed/9015311

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