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Mechanism of Inducible Nitric Oxide Synthase Exclusion from Mycobacterial Phagosomes

Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism. Here we report the mechanism underlying this process,...

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Detalles Bibliográficos
Autores principales: Davis, Alexander S, Vergne, Isabelle, Master, Sharon S, Kyei, George B, Chua, Jennifer, Deretic, Vojo
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134953/
https://www.ncbi.nlm.nih.gov/pubmed/18069890
http://dx.doi.org/10.1371/journal.ppat.0030186