Cargando…
Mechanism of Inducible Nitric Oxide Synthase Exclusion from Mycobacterial Phagosomes
Mycobacterium tuberculosis is sensitive to nitric oxide generated by inducible nitric oxide synthase (iNOS). Consequently, to ensure its survival in macrophages, M. tuberculosis inhibits iNOS recruitment to its phagosome by an unknown mechanism. Here we report the mechanism underlying this process,...
Autores principales: | Davis, Alexander S, Vergne, Isabelle, Master, Sharon S, Kyei, George B, Chua, Jennifer, Deretic, Vojo |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2007
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134953/ https://www.ncbi.nlm.nih.gov/pubmed/18069890 http://dx.doi.org/10.1371/journal.ppat.0030186 |
Ejemplares similares
-
Tuberculosis Toxin Blocking Phagosome Maturation Inhibits a Novel Ca(2+)/Calmodulin-PI3K hVPS34 Cascade
por: Vergne, Isabelle, et al.
Publicado: (2003) -
Role of phosphatidylinositol 3-kinase and Rab5 effectors in phagosomal biogenesis and mycobacterial phagosome maturation arrest
por: Fratti, Rutilio A., et al.
Publicado: (2001) -
Higher order Rab programming in phagolysosome biogenesis
por: Roberts, Esteban A., et al.
Publicado: (2006) -
Mycobacterial Mutants with Defective Control of Phagosomal Acidification
por: Stewart, Graham R, et al.
Publicado: (2005) -
Autophagy pathway intersects with HIV-1 biosynthesis and regulates viral yields in macrophages
por: Kyei, George B., et al.
Publicado: (2009)