Receptor-Binding and Oncogenic Properties of Polyoma Viruses Isolated from Feral Mice

Laboratory strains of the mouse polyoma virus differ markedly in their abilities to replicate and induce tumors in newborn mice. Major determinants of pathogenicity lie in the sialic binding pocket of the major capsid protein Vp1 and dictate receptor-binding properties of the virus. Substitutions at...

Descripción completa

Detalles Bibliográficos
Autores principales: Carroll, John, Dey, Dilip, Kreisman, Lori, Velupillai, Palanivel, Dahl, Jean, Telford, Samuel, Bronson, Roderick, Benjamin, Thomas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134959/
https://www.ncbi.nlm.nih.gov/pubmed/18085820
http://dx.doi.org/10.1371/journal.ppat.0030179

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2134959/
https://www.ncbi.nlm.nih.gov/pubmed/18085820
http://dx.doi.org/10.1371/journal.ppat.0030179

Ejemplares similares