Cargando…
SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE
A serologically reactive polysaccharide of dextran nature was produced from sucrose by the action of some enzyme or similar heat-labile agent contained in sterile filtered extracts derived from sucrose broth cultures of Leuconostoc mesenteroides. Rigorous controls were included to prove that this re...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
1942
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135250/ https://www.ncbi.nlm.nih.gov/pubmed/19871188 |
_version_ | 1782142852436852736 |
---|---|
author | Hehre, Edward J. Sugg, John Y. |
author_facet | Hehre, Edward J. Sugg, John Y. |
author_sort | Hehre, Edward J. |
collection | PubMed |
description | A serologically reactive polysaccharide of dextran nature was produced from sucrose by the action of some enzyme or similar heat-labile agent contained in sterile filtered extracts derived from sucrose broth cultures of Leuconostoc mesenteroides. Rigorous controls were included to prove that this reaction occurred in the absence of microorganisms. Purified preparations of the dextran formed by the sterile extracts were similar to the dextran elaborated in sucrose broth cultures of the bacteria in respect to both chemical and serological properties. The serological likeness was established not only by tests against leuconostoc antiserums but also by cross reactions with antiserums of Types 2, 20, and 12 pneumococci and by tests against a series of variously absorbed antiserums. |
format | Text |
id | pubmed-2135250 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1942 |
publisher | The Rockefeller University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-21352502008-04-18 SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE Hehre, Edward J. Sugg, John Y. J Exp Med Article A serologically reactive polysaccharide of dextran nature was produced from sucrose by the action of some enzyme or similar heat-labile agent contained in sterile filtered extracts derived from sucrose broth cultures of Leuconostoc mesenteroides. Rigorous controls were included to prove that this reaction occurred in the absence of microorganisms. Purified preparations of the dextran formed by the sterile extracts were similar to the dextran elaborated in sucrose broth cultures of the bacteria in respect to both chemical and serological properties. The serological likeness was established not only by tests against leuconostoc antiserums but also by cross reactions with antiserums of Types 2, 20, and 12 pneumococci and by tests against a series of variously absorbed antiserums. The Rockefeller University Press 1942-03-01 /pmc/articles/PMC2135250/ /pubmed/19871188 Text en Copyright © Copyright, 1942, by The Rockefeller Institute for Medical Research New York This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/). |
spellingShingle | Article Hehre, Edward J. Sugg, John Y. SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE |
title | SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE |
title_full | SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE |
title_fullStr | SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE |
title_full_unstemmed | SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE |
title_short | SEROLOGICALLY REACTIVE POLYSACCHARIDES PRODUCED THROUGH THE ACTION OF BACTERIAL ENZYMES : I. DEXTRAN OF LEUCONOSTOC MESENTEROIDES FROM SUCROSE |
title_sort | serologically reactive polysaccharides produced through the action of bacterial enzymes : i. dextran of leuconostoc mesenteroides from sucrose |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135250/ https://www.ncbi.nlm.nih.gov/pubmed/19871188 |
work_keys_str_mv | AT hehreedwardj serologicallyreactivepolysaccharidesproducedthroughtheactionofbacterialenzymesidextranofleuconostocmesenteroidesfromsucrose AT suggjohny serologicallyreactivepolysaccharidesproducedthroughtheactionofbacterialenzymesidextranofleuconostocmesenteroidesfromsucrose |