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STUDIES ON THE ANTIBACTERIAL ACTION OF THE SULFONAMIDE DRUGS : I. THE RELATION OFp-AMINOBENZOIC ACID TO THE MECHANISM OF BACTERIOSTASIS
The following observations have been made which substantiate the theory that the sulfonamide drugs used in the treatment of bacterial infections exert their bacteriostatic effect by competing with the essential metabolite, p-amino-benzoic acid, for an important enzyme site on the bacterial cell. 1....
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| Formato: | Texto |
| Lenguaje: | English |
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The Rockefeller University Press
1942
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2135255/ https://www.ncbi.nlm.nih.gov/pubmed/19871190 |