Targeting of U2AF(65) to Sites of Active Splicing in the Nucleus

U2AF(65) is an essential splicing factor that promotes binding of U2 small nuclear (sn)RNP at the pre-mRNA branchpoint. Here we describe a novel monoclonal antibody that reacts specifically with U2AF(65). Using this antibody, we show that U2AF(65) is diffusely distributed in the nucleoplasm with add...

Descripción completa

Detalles Bibliográficos
Autores principales: Gama-Carvalho, Margarida, Krauss, Randy D., Chiang, Lijian, Valcárcel, Juan, Green, Michael R., Carmo-Fonseca, Maria
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136214/
https://www.ncbi.nlm.nih.gov/pubmed/9166400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136214/
https://www.ncbi.nlm.nih.gov/pubmed/9166400

Ejemplares similares