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Insertional Mutation of the Drosophila Nuclear Lamin Dm(0 )Gene Results in Defective Nuclear Envelopes, Clustering of Nuclear Pore Complexes, and Accumulation of Annulate Lamellae

Nuclear lamins are thought to play an important role in disassembly and reassembly of the nucleus during mitosis. Here, we describe a Drosophila lamin Dm(0) mutant resulting from a P element insertion into the first intron of the Dm(0) gene. Homozygous mutant animals showed a severe phenotype includ...

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Detalles Bibliográficos
Autores principales: Lenz-Böhme, Bettina, Wismar, Jasmine, Fuchs, Silke, Reifegerste, Rita, Buchner, Erich, Betz, Heinrich, Schmitt, Bertram
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136230/
https://www.ncbi.nlm.nih.gov/pubmed/9166402