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A Dual-Specificity Phosphatase Cdc25B Is an Unstable Protein and Triggers p34(cdc2)/Cyclin B Activation in Hamster BHK21 Cells Arrested with Hydroxyurea

By incubating at 30°C in the presence of an energy source, p34(cdc2)/cyclin B was activated in the extract prepared from a temperature-sensitive mutant, tsBN2, which prematurely enters mitosis at 40°C, the nonpermissive temperature (Nishimoto, T., E. Eilen, and C. Basilico. 1978. Cell. 15:475–483),...

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Detalles Bibliográficos
Autores principales: Nishijima, Hitoshi, Nishitani, Hideo, Seki, Takashi, Nishimoto, Takeharu
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1997
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2136770/
https://www.ncbi.nlm.nih.gov/pubmed/9281587