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Influence of translation efficiency of homologous viral proteins on the endogenous presentation of CD8(+) T cell epitopes
A significant proportion of endogenously processed CD8(+) T cell epitopes are derived from newly synthesized proteins and rapidly degrading polypeptides (RDPs). It has been hypothesized that the generation of rapidly degrading polypeptides and CD8(+) T cell epitopes from these RDP precursors may be...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2137904/ https://www.ncbi.nlm.nih.gov/pubmed/17312009 http://dx.doi.org/10.1084/jem.20062508 |